Acclaimed for its outstanding acoustics, Twichell auditorium has hosted such famed artists as Tony Bennett, Chet Atkins, George Burns, Duke Ellington, Burl Ives, Itzhak Perlman, Yo Yo Ma, and Marilyn Horne.  Twichell is named as an historic John Philip Sousa site to commemorate the many performances given by Sousa and his band in the early twentieth century. Greeting visitors in front of the auditorium is the graceful 8-foot bronze sculpture of legendary contralto singer and civil rights pioneer Marian Anderson, created by artist Meredith Bergmann.

The auditorium is home to the Converse College Petrie School of Music concerts and operas, Converse convocations and special events, and also regularly welcomes community groups such as The Greater Spartanburg Philharmonic and Ballet Spartanburg for their performances.

Built in 1899 and renovated in 1989, Twichell has 1,500 seats and a 57-rank Casavant Freres organ with 2,600+ pipes.